Posts Tagged "menopause"

Where’s your focus?

Posted by on Jul 2, 2010 in Inspiration | 2 comments

Photographer Alex Prager was asked by the New York Times Supplement to do a photo shoot with women going through menopause. You can find the image that she captured here.

Alex described her assignment and the shot she got as follows:

“There were no rules – all they told me was they wanted pictures of older women and I could develop whatever concept I wanted; I had free rein…The taxi leaked and the rain machine was out of control. So she was soaked and miserable – but it made the shot…she was unhappy for real.”

It’s a beautiful photo and I encourage you to look at it. However, what strikes me is the focus on misery, unhappiness, and a haunting for something other than what “is.” Ironically, Prager says that she wanted the model to look backward, as if perhaps to imply that she longs for what was past and not what is ahead.

Are women in midlife longing for something else? Or are they now able to take life by the reins and reach or redefine personal goals?

Two weeks ago, I sat on a panel at Women Grow Business Bootcamp, a half-day conference devoted to empowering female entrepreneurs in their professional and personal lives. I spoke about evolution and the need to adapt to changes in one’s environment in order to continue to grow and attain goals. While  the context that day was on my business and marketing, the larger context was really life and the track that I’ve been on over the past 25 years, pausing to look over my shoulder but trying to keep my focus on the path ahead.

So, when I consider the question about longing, I realize that for the most part, my longing takes me forward and not backward. My visits to the past provide the foundation for my journey. However, a key factor remains true: as I’ve grown older, I do try to take more time to not only live my passion and personal/business goals but to live within them, meditating on what works and what doesn’t so that I can continue to move in a forward direction.

When was the last time you stepped back and asked yourself where your focus is?  Are you are looking ahead or consistently looking over your shoulder to see if you’ve caught up yet? What does your menopause and midlife look like so far?

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Ain’t no Wednesday Bubble: tick tock, part 2: the menopause blood test

Posted by on Jun 30, 2010 in fertility, menopause | 0 comments

I don’t usually  interrupt our regularly scheduled Wednesday Bubble but this one’s pretty hot off the presses. Researchers have once again confirmed that concentrations of the anti-Mullerian Hormone (AMH – a protein produced by cells in the ovary and controls follicle development) can help predict when a woman will develop menopause .

I wrote about AMH levels being used in this fashion in a post last year, so this current study simply helps to support the hypothesis that science is gaining ground in the fertility/post-fertility arena. Similar to previous studies, researchers collected blood samples from 266 women between the ages of 20 and 49, thereafter, measuring AMH levels. Additional blood samples were taken at three  yearly intervals, along with information about participants’ socioeconomic status and reproductive histories. The women also had physical exams every three years. The researchers then developed a mathematical model that would enable them to predict  average age of menopause based on varying levels of AMH throughout the reproductive years, and compared these estimates to age at actual menopause in a subgroup of 63 women.

Presenting the findings at the European Society of Human Reproduction meeting this past Monday, researchers say that they were able to predict actual age of menopause within a margin of error of only three to four years. Moreover, certain AMH levels at certain years of age could accurately predict whether or not a woman was likely to start menopause early, before age 45 or at a more common age, e.g. over age 50.

If AMH is confirmed as a marker in further testing, the researchers say that a blood test could help women start family planning early in their reproductive life. As I wrote previously, it could also be used as a strategy to start effective interventions geared towards ameliorating menopausal symptoms and age-related diseases at specific points in a woman’s life. However, the potential of such a test is not without the negative. I wonder if a blood test that accurately predicts menopause could be used against a woman trying to obtain insurance for a pregnancy gone wrong due to age at which she “should have conceived.” Only time can tell the risks and benefits of such a test. In the interim, it seems that science is well on its way to controlling the tick tock of every woman’s biological clock.

What do you think?

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Fat…to boldly go where where none has gone before

Posted by on Jun 28, 2010 in herbal medicine, weight gain | 2 comments

That body tire around the middle that tends to plague most women in their late forties and fifties and into old age reminds me of Star Trek – boldly going where no fat has ever gone before. Despite an hour at the gym daily, eating healthy and moderate (okay sometimes more than moderate) intake of alcohol, I still can’t seem to conquer that bulge that’s creeping into my midsection. I’ve spoken to trainers and nutritionists about it and have even tried conjugated linoleic acid (CLA), which theoretically helps reduce deposits of body fat. And still, fluctuating hormones and aging seem determined to redistribute that midsection bulge in ways that remain unacceptable (at least, to me). More importantly, however, is the fact that fat that settles in the abdominal areas increases the risk for impaired blood fat and insulin levels that can lead to diabetes and heart disease.

I’ve written about weight and the middle-aged bulge several times in the past and you can find some of these posts here. My friend Mollie Katzen and I collaborated on a post earlier this year about eating habits, food and midlife. And still, an effective solution to the bold bulge continues to elude women, trainers and researchers alike.

Still, a very small study published in the online edition of Menopause shows that hope may still spring eternal. In fact, results suggests that women who took 70 mg isoflavones daily (i.e. 44 mg daidzein, 16 mg glycitein, 10 mg genistein) for six months and then added at least an hour of intensive aerobics, circuit training and resistance training at least three times weekly for another six months experienced significant declines in blood pressure, fat mass and total body weight, and a small reduction in waist circumference (of about an inch and a half). In this particular study, the researchers selected women who were known to respond physically and beneficially to exercise. However, only the women who supplemented their exercise with isoflavones had demonstrable improvements in their fat mass and distribution. These women also experienced improvements in their insulin levels.

Clearly, the benefits of isoflavones added to exercise from both a weight and health perspective need to be explored more thoroughly and with larger numbers of women. However, it is possible that the addition of soy to a regular exercise routine may help to address that elusive bulge from entering the black hole that we call midlife.

Stay tuned!

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Wednesday Bubble: An ‘Evolutionary’ not ‘Revolutionary’ Rx for Hot Flashes?

Posted by on Jun 23, 2010 in menopause, new approaches | 2 comments

This week’s bubble brought to you by the manufacturers of Amberen™, a new menopausal treatment that bills itself as revolutionary not evolutionary. What they mean by this is that Amberen, a novel, non-hormal treatment for menopausal symptoms, does not represent an evolution of the same herbs (e.g. black cohosh, chaste berry) used by other manufacturers but a revolutionary new approach and strategy to addressing troublesome symptoms during menopause. Personally, I believe that anything that isn’t HRT based is evolutionary, however that aside, this week’s bubble is pretty darn solid and early data, pretty encouraging!

What is Amberen?

Amberen is a food supplement mostly composed of an enzyme known as succinate that is involved in metabolism. Dramatic swings in estrogen that result during menopause significantly affect the sensitive functioning of the  hypothalamic-pituitary-ovary (HPO) axis (part of the neuroendocrine system that regulates many processes in the body, including interactions between the glands and hormones).  According to published research, very small doses of succinate help to restore the way that the aging HPO axis functions, thereby promoting hormonal balance. In turn, this appears to boost estradiol levels and alleviate menopausal symptoms.

In small clinical studies, Amberen appeared to act as hormones in the body, resulting in self-reported reductions in the frequency of hot flashes, declines in insomnia and headache, and improvements in mood, anxiety and impaired sexual desire. Honestly, it sounds a bit too good to be true, so I am not entirely convinced. However, the researchers are quoted as saying that this approach to jump-starting HPO sensitivity could open the way for safer treatments for a variety of conditions, and not just menopause.

Amberen is not for everyone as it is not inexpensive, requiring at least a $90 commitment upfront (although there is an offer on the website for a 30 day free trial, a further dive shows that it takes at least 90 days to realize its full effects). However a three month on, three month off dosing schedule might be more convenient for women who have trouble remembering to take pills regularly.

Importantly, I did not see any reported details on side effects in the clinical studies I looked at, although the website cautions against women using Amberen if they have any thyroid or high blood pressure issues. I”d like to see more information on that as well.

Like any treatment for menopause, it’s essential to speak to your healthcare professional before diving in and trying Amberen. Personally, I’d like to see larger studies and specific information on side effects before making any real commitment to the product. However, I am intrigued by Amberen’s potential and certainly by this new approach to treatment, a seemingly viable and effective alternative to hormone replacement.

Have you tried Amberen? What do you think?

[Disclosure – I was approached by Amberen’s PR agency to see if I’d be interested in the product. After requesting and reviewing the clinical studies, I decided to write about it. I was not compensated for this piece nor was I sent or accepted any product.]

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Female Viagra hits a new low in the bedroom

Posted by on Jun 18, 2010 in sexual desire, sexual health | 4 comments

I was going to devote another post to “Low T’ and male “menopause” today.  Check back on Monday for that because the early news out of the Food and Drug Administration, whose Reproductive Health Advisory Committee is set to meet today to decide on a final verdict, is that flibanserin falls short of its promise to improve women’s sexual desire. Citing issues with the manufacturer’s data, the FDA says that studies do not show significant improvement in a woman’s sexual desire and also fails to note the significant side effects associated with flibanserin, including depression, dizziness and nausea. The ultimate decision could possibly deal a huge blow for profits that could exceed $2 billion dollars.

Importantly, it appears that hype about flibanersin (and more specifically, low sexual desire) has reached a new low. Not only have the company’s marketing efforts pushing the “fact” that one in 10 women suffer from low sexual desire (this figures varies in the medical literature), but the company even funded a Discovery Channel documentary to promote greater awareness of the disorder, a documentary that featured company-paid experts and was reviewed by the company before it aired.

As I’ve written time and again, low sexual desire is a serious and troublesome problem in women that can significantly affect quality of life, self-esteem and relationships. Some experts dispute that female sexual disorder even exists (although clinical experience in postmenopausal women speaks otherwise). However, whether or not you believe in low sexual desire, one thing remains true: when it comes to sex, women operate on a different plane than their male peers. Studies have shown that sexual desire in women is highly reliant on context, experience and personal attitudes. Therefore, you can’t simply fix the symptom without exploring underlying contributing factors.

Do we need another pill in the bedroom? Do we need a female viagra?  I hope that the FDA Reproductive Health Committee tells Boehringer “no.”

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