Search results for S-equol

Wednesday Bubble: Equol-ity

Posted by Liz on Nov 4, 2009 in herbal medicine, hot flash | 0 comments

Not bursting this one. At least not yet….

Last January, I shared some news on a key component in a type of isoflavone known as Daidzein. The component, S-equol, is produced by some people by the bacteria that lives in their intestines after eating soybeans and soy foods. Japanese women who produce S-equol naturally have been shown to have milder menopausal symptoms.

No wonder I was excited to see more information about S-equol coming out of September’s North American Menopause Society meeting. This time, researchers asked 320 postmenopausal women complaining of at least one hot flash a day to take a 10 mg equol supplement or a placebo tablet for 12 weeks. Menopausal symptoms were evaluated before and after taking the equol supplement, both by questionnaire and by a visual scale.

The findings are encouraging, as it appears that taking a daily equol supplement significantly reduced the frequency of hot flashes by as much as 58%. Women taking the supplement also reported declines in neck and shoulder stiffness. What’s more, no side effects were reported. However, while menopausal symptoms scores improved overall, S-equol did not appear to affect night sweats, mood issues or quality of life.

Obviously, S-equol is not yet available for mass consumption and only time will tell if these benefits can be duplicated in larger groups of women. Still, it’s nice to know that plant-based compounds are slowly proving their worth in the quest to find non-pharmaceuticals to alleviate menopausal symptoms. I’m all for equality when it comes to solutions for menopause and equol has my vote so far!

Soy-ta interesting….

Posted by Liz on Jan 30, 2009 in herbal medicine | 1 comment

A new study suggests that a key component of an isoflavone found in soy, confers significant improvements in mood-related symptoms in perimenopausal and postmenopausal women who lack the ability to produce this component on their own. The component, which is called S-equol, is involved in the metabolism of an isoflavone known as daidzein.

In this study, which appears  in the online edition of the journal Menopause, researchers randomly and blindly assigned 134 women to daily placebo, 10 mg of equol daily or 10 mg equol three times a day. All study participants also completed questionnaires at the study’s start and after the completion of the study on menopausal symptoms and moods. Additionally, they underwent physical exams and urine testing.

The results showed that women taking equol experienced significant declines in all menopausal mood symptoms except depression (although compared to women who were assigned placebo, the decline in depression was significant).

Overall, women taking equol showed significant declines in tension-anxiety and fatigue, and improvements in vigor scores. No side effects were noted, except for a rash in one woman taking equol.

These data suggest that supplementation with S-equol may help to improve mood-related symptoms in peri- and post-menopausal women. What’s more, the team concluded that equol supplementation may offer a promising alternative to estrogen therapy.

Sorta interesting, right?!