Wednesday Bubble: Maca what?
I love it when I run across an item that’s perfect for a Wednesday bubble; whether or not this one is “burstable” remains to be seen. There are accumulating data supporting the use of a Peruvian herb known as “Maca,” which reportedly balances hormones and consequently, alleviates certain perimenopausal symptoms.
In scientific communities, Maca is better known as Lepedium Meyenii (or more recently, Lepedium peruvianum Chacon ) and is a plant in the mustard family. In Norway, Maca is considered a medicinal substance and requires a prescription.
There have been a lot of claims about the aphrodisiac and energizing properties of Maca. For this reason alone, I am quite skeptical about whether or not the science behind the plant’s use in menopause is sound. Nevertheless, I did find several evidence-based, published studies examining Maca in peri- and post-menopausal women:
In two of the largest studies, a standardized, concentrated Lepedium peruvianum formulation (Maca-GO®) was compared to placebo tablet in 168 women who were in early post-menopause; treatment was provided for up to four months. Significant, beneficial changes were seen in balancing and normalizing hormones (estradiol, progesterone, follicular stimulating hormone and lutinizing hormone) and reducing menopausal symptoms, including hot flashes and night sweats.
In a much smaller, four-month study among perimenopausal women, all participants received Maca-GO® for two months and then a placebo tablet for two months. Two months of the active tablet resulted in anywhere from a 74% to 87% reduction in frequency of hot flashes and night sweats, as well as improvements in sleep interruption, nervousness, depression and heart palpitations. The authors, while acknowledging what is known as a placebo effect (i.e., “I want to believe it works so it does”) suggest that Maca-GO acts a hormonal toner. In this study, as in the one mentioned above, a balancing of hormonal levels was observed.
There is a new supplement called Femmenessence™ with two product lines – MacaPause for postmenopausal women and MacaLife for perimenopausal women. Like many other supplements, both claim to support the body’s ability to balance hormone and by default, address the many troublesome symptoms associated with menopause. Recommended dosage is twice-daily 500 mg capsules for the first four months with a one week break every two to three months. The manufacturer also recommends that women first speak to a healthcare practitioner before using Femmenessence.
As I’ve written time and again, the one-size fits all’ framework doesn’t work too well when it comes to hormones, let alone any other disease. Nevertheless, I am curious about Maca. What about you? Have you heard of or tried Maca? What were the results?
Read MoreOne size fits all
Like Zappa, I’ve never been one to be confined to a box. Or to be so presumptuous to believe that I am like any other woman out there (except, perhaps my mother but that’s an entirely different topic!). So why do manufacturers continue to assume that a single neutraceutical or combination supplement is going to address all of the major attributes of perimenopause, e.g., hot flashes AND night sweats AND mood swings AND sexual desire and so on and so on and so on? Am I missing something here?
One of the reasons I continue to encourage women to speak to a licensed practitioner is so that they can obtain advice that is individualized and personalized to their unique needs. I may be having night sweats every other night and regularly waking at 3 am, while you might be experiencing hot flashes every two hours. Should we believe that a single pill that combines, say, isoflavones, black cohosh and chaste berry will be helpful for both of us?
So, once again, I was dumbstruck when I ran across a site for yet another menopausal supplement: Menozac™, your one-stop pill for:
- hot flashes
- night sweats
- vaginal dryness
- forgetfulness
- mood swings
- bloating
- anxiety
- emotional issues (which in turn, will benefit sexual issues)
Have you tried Menozac™? Was it “all that and more?” Did you “graduate to maturity and being free of the responsibility of being fertile?” Did Mother Nature’s “helper” save you from being bedeviled by the menopause?
I swear, I didn’t write this copy. I simply took poetic license with it. In fact, it’s so “all that” that I don’t believe that I am creative enough to come up with the degree of hype that permeates each sentence.
Dear readers – please be safe, be diligent, do your homework and make conscious decisions. Be skeptical. Be suspicious. Ask questions. Speak to a trained expert. Read. Explore.
One size does not fit all.
Read MoreWednesday Bubble: Black cohosh strikes again…
I’m beginning to see a pattern in my Wednesday Bubble posts. It certainly is not deliberate. But there’s more good news about black cohosh and I’d like to share it.
A Yale School of Medicine researcher and physician has presented findings of a web-based survey examining the use of Remifemin black cohosh standardized extract among 692 women, ages 35 to 45. The study results, which were displayed this week at the American College of Obstetrics and Gynecology annual meeting, demonstrate that women are using black cohosh to avoid HRT. Okay, no big news there; I’ve posted about the utility of standardized black cohosh in lieu of HRT for almost a year now.
However, not only did almost 90% of women report being satisfied or highly satisfied with black cohosh, but approximately 88% noted that they felt it was effective or very effective for treating their symptoms.
More importantly, however, the study revealed that women are discussing the use of this standardized form of black cohosh with their health practitioners (mostly ob/gyns or family doctors). And, over half — an estimated 53.7% — said that their physicians were supportive of their decision to use black cohosh.
Personally, I find these results very encouraging; not only do they support a long-standing contention that black cohosh, namely Remifemin, is effective for hot flashes, night sweats, and other perimenopausal symptoms, but they also provide evidence that the communication channels between menopausal women and their practitioners are starting to open.
Notably, black cohosh is one of the few herbs that has been consistently shown to alleviate vasomotor symptoms like hot flashes and night sweats. Although there has been some questions about its safety, particularly with regards to liver toxicity, there are accumulating data disputing some of these claims. Indeed, at this year’s ACOG meeting, another researcher examined and compared liver function in 142 patients taking standardized black cohosh extract and 138 taking placebo and found no statistically sigificant changes in liver function. Moreover, analysis of a smaller group of with abnormal liver function values found only one case where there was a significant difference between the groups. This led the researchers to conclude that standardized black cohosh, namely Remifemin, can be used safely.
Personally, I’ve been using Remifemin for over a year now. Recommended by a health practitioner and endorsed by my Ob/Gyn, along with a variety of other Chinese and Western herbs, I’ve been fortunate and have found significant relief from night sweats.
Like any herbal preparation, be sure to speak with a health practitioner who is certfied in practicing herbal medicine and can monitor your progress to insure that your regimen is safe and effective. But it is wonderful to know that traditional Western practitioners may be finally opening their eyes to HRT alternatives. Bravo!
Read MoreErring on the side of black cohosh
I’ve written quite a few posts about black cohosh over the past year. Black cohosh (better know in the plant circles as Actaea racemosa and cimicifuga racemosa) is an herb shown to treat vasomotor symptoms such as hot flashes, night sweats and mood swings. Yet, concerns have been raised about its possible link to liver disease and toxicity.
Thus far, the evidence against black cohosh has been pretty lean. I’m happy to add a few more coals to that particular fire.
In a case report published in the Ahead of Print section of Menopause, researchers present evidence on nine cases of suspected liver toxicity in women who had used black cohosh.
The result: they excluded an potential link between the women’s symptoms and ingestion of black cohosh in eight of nine cases. In one case, they reported a possible association to liver disease for an unknown brand of black cohosh taken for two months but also state that the woman had factors that might have skewed the results.
They concluded that significant circumstantial evidence linking black cohosh to liver toxicity is missing.
Although this is a very small study, this is not the first time that upon examination, a lack of causality was found between black cohosh and liver disease. Of course, standardized formulations are a must, as is guidance from a healthcare professional who is well-versed in the use of herbs for menopause. Nevertheless, I am hopeful that eventually, black cohosh will become a respectable player in the field.
Read MoreSt John’s Wort, Quality of Life & Hot Flashes
Can St. John’s Wort improve quality of life during perimenopause?
While the benefit of St. John’s wort for treatment depression and other mood disorders remains inconclusive, there is new evidence that it might be useful for symptoms of perimenopause that affect quality of life, namely hot flashes.
In a small study published in the February 3 Advanced Edition of Menopause, researchers randomly assigned 47 perimenopausal women experiencing 3 to 5 hot flashes daily to 900 mg St. John’s Wort extract three times daily or placebo. All study participants were asked to keep daily diaries noting the frequency and intensity of their hot flashes. Quality of life and hot flashes scores were also calculated.
At three months, women who had been taking St. John’s Wort reported significant improvements in menopause-specific quality of life and significantly fewer sleep problems. They also experienced improvements in daily hot flash frequency and hot flash scores.
Although the researchers caution that this is small study and that larger trials are needed,they say that St. John’s Wort may improve quality of life in ways that are important to perimenopausal women.
About St. John’s Wort
In addition to controversy over its effectiveness in treating depression, experts recommend against taking St. John’s Wort at the same time as alcohol, narcotics, amphetamines, tyrosine supplements, flu medicines and foods containing tyramine (e.g. yeast, aged cheese, eggplant, soy sauce). St. John’s Wort can also interact with prescription antidepressants, oral contraceptives and certain medications that thin the blood. More information about St. John’s Wort, its side effects and risks can be found here.
As with any herbal preparation, it’s critical to speak to a healthcare practitioner before embarking on therapy. Acupuncturist and Chinese Medicine Specialist Elaine Stern has a few tips with regards to what you should look for.
In the interim, keep an eye out for more news about St. John’s Wort. These results are encouraging news for hot flashers!
Read MoreSoy-ta interesting….
A new study suggests that a key component of an isoflavone found in soy, confers significant improvements in mood-related symptoms in perimenopausal and postmenopausal women who lack the ability to produce this component on their own. The component, which is called S-equol, is involved in the metabolism of an isoflavone known as daidzein.
In this study, which appears in the online edition of the journal Menopause, researchers randomly and blindly assigned 134 women to daily placebo, 10 mg of equol daily or 10 mg equol three times a day. All study participants also completed questionnaires at the study’s start and after the completion of the study on menopausal symptoms and moods. Additionally, they underwent physical exams and urine testing.
The results showed that women taking equol experienced significant declines in all menopausal mood symptoms except depression (although compared to women who were assigned placebo, the decline in depression was significant).
Overall, women taking equol showed significant declines in tension-anxiety and fatigue, and improvements in vigor scores. No side effects were noted, except for a rash in one woman taking equol.
These data suggest that supplementation with S-equol may help to improve mood-related symptoms in peri- and post-menopausal women. What’s more, the team concluded that equol supplementation may offer a promising alternative to estrogen therapy.
Sorta interesting, right?!
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