Wednesday Bubble: Blue

Posted by on Oct 15, 2008 in emotions | 3 comments

[youtube=http://www.youtube.com/watch?v=_LhwlsaA-Vc]

Mid-life depression is a real issue. But are your blue feelings due to depression or to menopause? That is, is depressed mood in middle aged women a result of aging and some of the emotional or pyschological factors that accompanies it, or due to hormonal changes during the transition?

Experts still are not certain of the association and to date, research has demonstrated contradictory results, with some studies showing a correlation between depression and menopause and others, none. Other studies suggest mood declines during early stages of menopause followed by improvements as vasomotor and other symptoms start to wane.

However, what the data do appear to show is that there are several time periods in a woman’s life in which she is more vulnerable to depressive symptoms, e.g., pre-menstruation, postpartum and of course, during the menopausal transition.  What’s more, data from the Melbourne Women’s Mid-Life suggest that a prior history of depression and having negative feelings about menopause can increase risk. Additionally, menopausal-onset depression and the start of vasomotor symptoms during the early stages of menopause appear to be linked.

Personally, I believe that drastic changes in one’s body, in moods and appearance, as well as some serious self-exploration and self-analysis, also play a role.

So, what can you do when you feel blue?

Transdermal estrogen delivered via a patch that is applied to the skin appears to even out estrogen fluctuations that may affect mood during the menopause. For women for whom estrogen is not an option and who are not interested in trying antidepressants, (whose effects, btw, may vary depending on age), St. John’s Wort (hypericum) extract may be a viable and effective option. A recent analysis of 29 studies enrolling almost 5,500 patients showed that St. John’s Wort extract:

  • is superior to placebo tablets in patients with major depression
  • is as effective as standard antidepressants
  • has fewer side effects than standard antidepressants

So, how should you take St. John’s Wort? Well, like any herb, it’s best to consult with a practitioner well-versed in herbal therapy rather than reaching for a bottle in your local drugstore. Many therapists are also joining the band wagon and may be able to provide advice.

In earlier posts, I wrote how exercise can help to improve mood symptoms. And ironically, a glass of red wine daily also has been shown to improve mood and quality of life, although if you’re taking medications for depression, alcohol is counterintuitive.

So, tell me? Are you feeling blue on a more regular basis? What seems to help (or not help)?

3 Comments

  1. 10-15-2008

    Suggestion:

    If you are taking other meds, notify your health-care provider before you try St. John’s Wort. There can be interactions. Never mix with other anti-depressants.

  2. 10-15-2008

    Great point Dr. Hubbard. I did see some drug-drug interactions in the data. But I do believe that no one should take SJW without talking to someone first to insure proper dosing/administration.

  3. 10-16-2008

    This is interesting. I am not yet going through menopause, but when I read about a lot of the initial mental/emotional “symptoms” it sounds a lot like depression. Informative post – good job!

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