A new study suggests that a key component of an isoflavone found in soy, confers significant improvements in mood-related symptoms in perimenopausal and postmenopausal women who lack the ability to produce this component on their own. The component, which is called S-equol, is involved in the metabolism of an isoflavone known as daidzein.
In this study, which appears in the online edition of the journal Menopause, researchers randomly and blindly assigned 134 women to daily placebo, 10 mg of equol daily or 10 mg equol three times a day. All study participants also completed questionnaires at the study’s start and after the completion of the study on menopausal symptoms and moods. Additionally, they underwent physical exams and urine testing.
The results showed that women taking equol experienced significant declines in all menopausal mood symptoms except depression (although compared to women who were assigned placebo, the decline in depression was significant).
Overall, women taking equol showed significant declines in tension-anxiety and fatigue, and improvements in vigor scores. No side effects were noted, except for a rash in one woman taking equol.
These data suggest that supplementation with S-equol may help to improve mood-related symptoms in peri- and post-menopausal women. What’s more, the team concluded that equol supplementation may offer a promising alternative to estrogen therapy.
Sorta interesting, right?!
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I am glad to see researchers looking into soy’s effective again because it seems like the media has been giving soy a bad rap lately. Another good article about soy and menopause is this one from Women to Women — Soy for menopause