Got botanicals? You might want to get this one. Although the traditional Japanese medicine Kampo supplement TU-025 doesn’t appear to offer much hope in the hot flash department, a well-known botanical supplement widely used in Korea, EstroG-100, may. In fact, it appears that the proprietary blend of Korean herbs in EstroG-100, including Cynanchum wilfordii, Phlomis ubrosa and Angelica gigas are not only safe but help in a number of menopausal symptoms in addition to hot flashes.
So, what’s the lowdown on EstroG-100? Basically, the supplement has been studied in Asian women and we know from other alternative strategies that effectiveness among different ethnicities don’t always translate. Hence, I was pretty interested to learn that researchers decided to see if EstroG-100 would work on menopausal symptoms in a small group of white- and non-White Hispanics and African American women who were pre-, peri or menopausal. Over a three month time period, women either took 2 EstroG-1oo tablets or placebo twice daily and then using a scientific index, self-reported and rated symptoms, including:
- hot flashes
- cold swewats
- numbness, tingling
- insomnia
- nervousness, depression or feeling blue
- dizziness
- fatigue
- muscle and joint pain
- headache
- pounding heart
The study results suggest that EstroG-100 is not only safe, but it has a significant impact on a few very troublesome symptoms, namely hot flashes and sweats, insomnia, nervousness, feeling blue, dizziness and fatigue. Overall, menopausal symptom scores declined by more than half in women using EstroG-100 compared to women taking placebo. Moreover, initial, favorable changes were seen as early as 6 weeks. Estro-G also appeared to have a beneficial effect on the severity of vaginal dryness, a condition that plagues many menopausal women as estrogen levels decline. Even better were findings that EstroG-100 does not have any sort of estrogenic effect, indicating that it may potentially be safely used in women at risk for gynecological cancers. And, use of EstroG-100 does not appear to affect weight, body mass index or liver enzymes, all of which are affected by hormone replacement.
Less clear is how EstroG-100 will work in non-Hispanic white women and that study, along with studies in larger numbers of women may determine it’s overall benefit in menopause. Meanwhile, I’m pretty encouraged. This study addresses a lot of complaints about studies of alternatives; it is well designed, randomized, looks closely at adverse events and includes a variety of ethnic groups and menopausal status. Stay tuned for more on EstroG-100. This botanical may be here to stay!
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